| 双丙氨磷发酵过程变温控制的研究 |
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| 引用本文： | 曲志西,狄小青,张勍,张庆连.双丙氨磷发酵过程变温控制的研究[J].河北化工,2009,32(10):17-18,40. |
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| 作者姓名： | 曲志西 狄小青 张勍 张庆连 |
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| 作者单位： | 华北制药集团爱诺有限公司,河北,石家庄,052165 |
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| 摘 要： | 为了考察不同温度对双丙氨磷的发酵影响,采用摇瓶发酵,改变发酵温度,来确定较为适合的发酵工艺。结果表明,双丙氨磷吸湿链霉菌的菌丝最佳生长温度是28℃,产物的最佳合成温度是26℃。采用变温控制方案,双丙氨磷终产物比恒温培养提高了11.7%。
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| 关 键 词： | 双丙氨磷 吸湿链霉菌 发酵 变温控制 |
Study on Temperature-control in Bialaphos Fermentation |
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| QU Zhi-xi,DI Xiao-qing,ZHANG Qing,ZHANG Qing-lian.Study on Temperature-control in Bialaphos Fermentation[J].Hebei Chemical Engineering and Industry,2009,32(10):17-18,40. |
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| Authors: | QU Zhi-xi DI Xiao-qing ZHANG Qing ZHANG Qing-lian |
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| Affiliation: | (North China Pharmaceutteal Group Aino Co., Ltd,Shijiazhuang 052165, China) |
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| Abstract: | In order to investigate the effect of temperature-control in the process of Bialaphos fermentation,The best fermentation change cultivation temperatures in shake flasks fermentation.The results show that the mycelium optimal propagate temperatures of Streptomyces hygroscopicus is 28 ℃,and the yield optimal synthesis temperatures is 26 ℃.The Bialaphos production increased by 11.7% according to the temperature-control. |
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| Keywords: | Bialaphos Streptomyces hygroscopicus fermentation temperature-control |
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