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The clinico-immunological parallels of hemosorption using different sorbents in the treatment of bronchial asthma patients
Authors:IuIa Tkachenko
Abstract:A comprehensive clinical and functional and allergo-immunological comparative evaluation was done of hemosorption involving the KAU, SKN hemosorbents, "Gemosfer" and a DNA-containing sorbent in 341 patient with bronchial asthma. SKN sorbent were found out to have a more pronounced positive effect on clinical signs and functional activity of immunocompetent cells. The above sorbents appeared to significantly enhance sensitivity of bronchial beta-adrenoreceptors; besides, they allow the dosages of systemic corticosteroids to be substantially brought down. The KAU and "Gemosfer" hemosorbents caused, to a certain degree, a blockade of the phagocyte system of blood, and, to a considerably lesser extent, affected the level of autoimmune processes. Thus, hemosorption should involve SKN sorbents or an SKN-based DNA-containing sorbent.
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