| 局部麻醉药物利多卡因的微分脉冲吸附溶出伏安法测定 |
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| 引用本文： | 刘澄凡,郭寿春,张亚利,焦奎.局部麻醉药物利多卡因的微分脉冲吸附溶出伏安法测定[J].青岛科技大学学报,1991(3). |
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| 作者姓名： | 刘澄凡 郭寿春 张亚利 焦奎 |
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| 作者单位： | 青岛化工学院应化系，青岛市肿瘤医院，青岛化工学院应化系，青岛化工学院应化系 |
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| 基金项目： | 国家教委优秀年轻教师基金 |
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| 摘 要： | 用微分脉冲吸附溶出伏安法测定了利多卡因针剂的含量。在1×10~(-7)～3×10~(-4)mol/l内浓度与波高呈线性关系。最低检测限为1×10~(-8)mol/l。回收率为98.07±0.05％。方法准确、简便、灵敏。
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| 关 键 词： | 局部麻醉药 微分脉冲伏安法 吸附溶出伏安法 |
Determination of Local Anaesthetics Lidocaine by Differential Pulse Adsorptive Stripping Voltammetry |
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| Liu Chengfan Guo Shouchun Zhang Yali Jiao Kui.Determination of Local Anaesthetics Lidocaine by Differential Pulse Adsorptive Stripping Voltammetry[J].Journal of Qingdao University of Science and Technology:Natutral Science Edition,1991(3). |
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| Authors: | Liu Chengfan Guo Shouchun Zhang Yali Jiao Kui |
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| Affiliation: | Department of Applied Chemistry |
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| Abstract: | Preconcentration and quantity determinations of the local anaesthetics lidocaine are accomplished by adsorption of the drug at a hanging mercury drop electrode and differential pulse voltammetric analysis. By simply immersing the electrode in 0.1mol/1 NaOH of lidocaine sample for a 3-min period and then recording stripping curves, sensitivities well below 10~(-8)mol/l are readily achieved. The linear concentration range is found to be from 1×10~(-7) to 3×10~(-4)mol/l. This method has been applied to the determination of lidocaine in ampoules with a satisfactory result. |
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| Keywords: | lidocaine differential pulse voltammetry adsorptive stripping voltammetry |
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