氨基磺酸催化甲醛和甲酸甲酯偶联反应的研究

在釜式反应器中研究了氨基磺酸催化甲醛和甲酸甲酯偶联反应，考察了反应温度、反应时间、原料配比和催化剂用量等因素对乙醇酸甲酯和甲氧基乙酸甲酯生成量的影响，最佳反应条件为: 反应温度150～160 ℃，反应时间4 h，n（甲醛）：n（甲酸甲酯）=05，在此条件下得到最大的乙醇酸甲酯和甲氧基乙酸甲酯的生成量，总生成量达到2134 mmol·(g-cat)-1。与其他催化剂的性能进行对比发现，氨基磺酸对催化甲醛和甲酸甲酯偶联反应显示出较好的催化性能。

Coupling of formaldehyde and methyl formate catalyzed by aminosulfonic acid

Coupling of formaldehyde and methyl formate using aminosulfonic acid as a catalyst was studied in an autoclave reactor, including influence of reaction temperature, reaction time, reactants ratio and catalyst dosage on the yield of methyl glycolate(MG) and methyl methoxy acetate(MMAc). The optimal reaction condition was obtained as follows: 150-160 ℃, reaction time 4 h, n(formaldehyde)∶n(methyl formate)＝0.5, with overall yield of 21.34 mmol·(g-cat)^－1.