西洋参片对小鼠抗疲劳作用的实验研究

目的：研究西洋参片的抗疲劳作用。方法：将小鼠按体重随机分为对照组和低、中、高剂量组。低、中、高三个剂量组分别灌胃给予67、133、200mg／kg的西洋参片30d，对照组给蒸馏水。测定小鼠游泳时间及血乳酸、尿素氮、肝糖原等指标。结果：西洋参片的三个剂量组均能显著提高小鼠肝糖原的储备量；降低小鼠游泳后血乳酸曲线下面积；降低运动后血清尿素氮含量，加速体内尿素氮的清除速率，提高小鼠的游泳时间。结论：西洋参片具有抗疲劳作用。

Experimental Study of Panax quiquefolium tablet on the Anti-fatigue Effect in Mice

Objective To study of Panax quiquefolium tablet on the anti-fatigue effect in mice. Method: Mice were randomly assigned to control group, low dose, middle dose and high dose experimental groups according to their body weights. Panax quiquefolium tablet were administered in experimental groups at doses of. 67, 133, 200mg/kg. The control mice were given water. After 30 days., the swimming test were carried out and the death time was observed and recorded, after the mice swimming for a period the blood were taken for determining Blood Urea Nitrogen (BUN) and Serum Lactic-acid. The liver were taken for determining the glycogen. Results: 67, 133, 200mg/kg dose could significantly prolonged swimming time, reduce BUN level , increased the liver glycogen storage and accelerate lactic-acid clearance after swimming. Conclusion: Panax quiquefolium tablet could alleviate physical fatigue in mice.