时间分辨反射确定生物组织光学参数的研究

从半无限大生物组织出发．研究了从总时间分辨反射确定组织光学参数的方法：将总时间分辨反射漫射理论的结果与Monte Carlo模拟的结果进行了比较．零边界条件(ZBC)和外推边界条件(EBC)的漫射方程对Monte Carlo模拟的数据作非线性拟合确定了约化散射系数和吸收系数．对所确定的光学参数误差作了较详细的分析。研究结果表明．两个漫射模型确定吸收系数的误差小于10％，采用EBC的模型拟合约化散射系数其误差与光学参数有关，ZBC则产生较大的误差。

Study of Determinating Optical Properties of Biological Tissue from Resolved-time Reflectance

Total time-resolved reflectance calculated based on the diffusion theory with zero-boundary conduction(ZBC) and extrapolated-boundary conduction(EBC) in semi-infinite biological tissue are compared with Monte Carlo simulations.The corresponding diffusion equations are fitted to Monte Carlo simulations data for determining the optical parameters of tissues.It is shown that the errors in the absorption coefficients derived from two the diffusion models are smaller than 10 %,the errors in reduce scattering coefficients derived from the diffusion model with EBC relate to the optical parameters of tissues,whereas,the errors in reduce scattering coefficients are large for different optical parameters when ZBC is used.