| 近红外无创血糖测量的研究 |
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| 引用本文： | 陈民森,陈文亮,杜振辉,徐可欣,蒋诚志.近红外无创血糖测量的研究[J].现代仪器,2004,10(4):38-40. |
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| 作者姓名： | 陈民森 陈文亮 杜振辉 徐可欣 蒋诚志 |
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| 作者单位： | 天津大学精密测试技术及仪器国家重点实验室,天津,300072 |
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| 基金项目： | 国家自然科学基金 ( 3 0 170 2 61) |
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| 摘 要： | 本文分析了光在手掌组织中的传播特性 ,以及经皮近红外无创血糖浓度测量原理。基于AOTF (声光可调谐滤波器 )分光系统 ,构建了近红外经皮无创血糖检测系统 ,并利用该系统对 3名健康青年志愿者进行OGTT (口服葡萄糖耐量试验 )实验 ,得到较好的测量结果。三次实验中PLS (偏最小二乘 )校正集模型的RMSEP (预测均方根误差 )分别为 0 6 9mmol/L、 0 4 9mmol. /L、 0 5 4mmol/L。
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| 关 键 词： | 近红外 经皮的 无创血糖检测 |
Study on non-invasive blood glucose detection by near-infrared spectroscopy |
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| Chen Minsen Chen Wenliang Du Zhenhui Xu Kexin Jiang Chengzhi.Study on non-invasive blood glucose detection by near-infrared spectroscopy[J].Modern Instruments,2004,10(4):38-40. |
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| Authors: | Chen Minsen Chen Wenliang Du Zhenhui Xu Kexin Jiang Chengzhi |
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| Abstract: | The character of light propagation in palm tissue is explained,and the principle of non-invasive blood glucose detection through transcutaneous near-infrared spectroscopy is present.Based on AOTF(Acousto-Optic Tunable Filter)spectroscopic system,measurement system for transcutaneous near-infrared(NIR)spectroscopy is established.Using our proposed NIR measurement system,OGTT(Oral Glucose Tolerance Test)experiments were performed to 3 young healthy volunteers,and the RMSEPs(Root Mean Square Error of Prediction)of PLS(Partial Least Square)calibration models were 0.69mmol/L,0.49mmol/L and 0.54mmol/L. |
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| Keywords: | Near-infrared Transcutaneous Non-invasive blood glucose detection |
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