Genetic variability of human plasma and erythrocyte lipids |
| |
Authors: | K W Kang G E Taylor J H Greves H L Staley Joe C Christian |
| |
Affiliation: | (1) Department of Medical Genetics, Indiana University Medical School, 46202 Indianapolis, Indiana |
| |
Abstract: | Genetic variation of fasting plasma lipids, lipoproteins and erythrocyte membrane lipids was studied in 67 sets of like-sexed
twins and 3 sets of triplets. All of the plasma lipids were more variable in dizygotic twins than monozygotic twins with the
exception of phosphatidyl ethanolamine, but only cholesteryl esters, lecithin, phosphatidyl inositol and β-lipoprotein showed
significant genetic variation. In contrast, no significant genetic variability was found in any of the erythrocyte membrane
lipids and erythrocyte phosphatidyl ethanolamine had significantly greater variation in monozygotic twins. Two sets of twins
had an extra lipoprotein band (slow α1); in one family the variant appeared to be segregating as a dominant trait.
Presented in part at the ISF-AOCS World Congress, Chicago, September 1970. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|