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Phytochemistry, nutritional and pharmacological properties of Artocarpus heterophyllus Lam (jackfruit): A review
Authors:Manjeshwar Shrinath Baliga  Arnadi Ramachandrayya ShivashankaraRaghavendra Haniadka  Jerome DsouzaHarshith P. Bhat
Affiliation:
  • a Department of Research and Development, Father Muller Medical College, Father Muller Road, Kankanady, Mangalore 575003, Karnataka, India
  • b Department of Biochemistry, Father Muller Medical College, Father Muller Road, Kankanady, Mangalore 575003, Karnataka, India
  • c Father Muller Medical College, Father Muller Road, Kankanady, Mangalore 575003, Karnataka, India
  • d Research Centre, Maharani Lakshmi Ammani Women''s College, Malleswaram 18th Cross, Bangalore 560012, Karnataka, India
  • Abstract:Artocarpus heterophyllus Lam, commonly known as the jackfruit tree and belonging to the family Moraceae, is an exotic tree originally native to the Western Ghats of India. The fruits are of dietary use and are an important source of carbohydrate, protein, fat, minerals and vitamins. The heart wood is a very durable timber and is used in the preparation of furniture. The bark, roots, leaves, and fruit are attributed with diverse medicinal properties and are used in the various traditional and folk systems of medicine to treat a range of ailments. Preclinical studies have shown that jackfruit possesses antioxidant, anti-inflammatory, antibacterial, anticariogenic, antifungal, antineoplastic, hypoglycemic, wound healing effects and causes a transient decrease in the sexual activity. Clinical studies have also shown that the decoction of the leaves possesses hypoglycemic effects in both healthy individuals and non-insulin-dependent diabetic patients. Phytochemical studies have shown that jackfruit contains useful compounds like the flavonoids, sterols and prenylflavones which may have been responsible for the various pharmacological properties. The present paper reviews the nutritional value, culinary uses, the phytochemical compounds, traditional usage and validated pharmacological properties of jackfruit.
    Keywords:ABTS, 2, 2&prime  -azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)   ALT, Alanine aminotransferase   AST, Aspartate aminotransferase   COX-2, Cyclooxygenase-2   DPPH, 1,1-diphenyl-2-picrylhydrazyl   EDTA, Ethylenediaminetetraacetic acid   FRAP, Ferric Reducing Antioxidant Power   iNOS, Inducible nitric oxide synthase   LPS, Lipopolysaccharides   MIC, Minimum inhibitory concentration   DMPD, N-dimethyl-p-phenylendiamine   NO, Nitric oxide   PGE2, Prostaglandin E2
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