Abstract: | Forty-nine derivatives of dimethyldithiocarbamic acid: dimethyldithiocarbamoylamides, N-(dimethyl- dithiocarbamoylalkyl)-amides, -acid esters and -ethers and related compounds were synthesised and tested for fungitoxicity. Of the amides, only those compounds that readily split off the dimethyl-dithiocarbamate ion, detected by a brown colour with copper acetate, had high activity against Venturia inaequalis. Of six ethylenebis-S-alkanamidoalkyl dithiocarbamates, all of which readily yielded the ethylenebisdithiocarbamate ion, only those with a trichloromethyl substituent had high activity. Of the other new condensation products of N-(l,2,2,2-tetrachloroethyl)amides with various nucleophiles, only the 8-oxinate was highly active. |