A method for selecting drugs that affect the rheological properties of the blood in vitro

For the selection of compounds affecting the hemorrheologic status a method for reproducing disorders of blood rheologic properties in vitro was developed. It consists in 60-min incubation of blood at 42 degrees C. The hemorrheologic effect of quercetin under such conditions was studied and a dependence of the effect of quercetin on blood viscosity and red cell aggregation on the drug concentration was revealed.