Coronary Artery Ectasia: Review of the Non-Atherosclerotic Molecular and Pathophysiologic Concepts |
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| Authors: | Gavin H C Richards Kathryn L Hong Michael Y Henein Colm Hanratty Usama Boles |
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| Affiliation: | 1.Cardiovascular Research Institute (CVRI) Dublin, Mater Private Hospital, D07 WKW8 Dublin, Ireland; (G.H.C.R.); (K.L.H.); (C.H.);2.School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland;3.Department of Public Health and Clinical Medicine, Heart Clinic, Umea University, 901 87 Umea, Sweden;4.Cardiology Department, Tipperary University Hospital, E91 VY40 Clonmel, Ireland |
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| Abstract: | Coronary artery ectasia (CAE) is frequently encountered in clinical practice, conjointly with atherosclerotic CAD (CAD). Given the overlapping cardiovascular risk factors for patients with concomitant CAE and atherosclerotic CAD, a common underlying pathophysiology is often postulated. However, coronary artery ectasia may arise independently, as isolated (pure) CAE, thereby raising suspicions of an alternative mechanism. Herein, we review the existing evidence for the pathophysiology of CAE in order to help direct management strategies towards enhanced detection and treatment. |
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| Keywords: | coronary artery ectasia coronary artery aneurysm CAD cytokine lipidome |
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