| 5-溴-2-甲氧基苯酚的合成 |
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| 引用本文： | 陈正许,蒋成君.5-溴-2-甲氧基苯酚的合成[J].浙江化工,2011,42(10):6-8. |
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| 作者姓名： | 陈正许 蒋成君 |
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| 作者单位： | 1. 浙江新东港药业股份有限公司,浙江台州,318000
2. 浙江科技学院生物与化学工程学院,浙江杭州,310023 |
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| 基金项目： | 浙江省重点科技创新团队项目 |
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| 摘 要： | 5-溴-2-甲氧基苯酚是一种重要的农药、医药中间体，本文以邻甲氧基苯酚为原料，乙酰化、溴化、脱保护得到5-溴-2-甲氧基苯酚，总收率为64．3％，产物的结构通过1HNMR、13CNMR及元素分析进行验证。
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| 关 键 词： | 邻甲氧基苯酚 溴化 5-溴-2-甲氧基苯酚 脱保护 |
Synthesis of 5-Bromo-2-Methoxyphenol |
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| CHEN Zheng-xu,JIANG Cheng-jun.Synthesis of 5-Bromo-2-Methoxyphenol[J].Zhejiang Chemical Industry,2011,42(10):6-8. |
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| Authors: | CHEN Zheng-xu JIANG Cheng-jun |
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| Affiliation: | 1.Zhejiang New-Dankong Pharm.Co.,Ltd.,Taizhou 318000,China;2.Zhejiang University of Science and Technology,Department of Biological and Chemical Engineering,Hangzhou 320023,China) |
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| Abstract: | 5-bromo-2-methoxyphenol was synthesized from guaiacol via protection of phenolic hydroxyl group, bromination with bromine, and deprotection, with the overall yield of 64.3%. The structure of the product was confirmed by 1HNMR, 13CNMR and elementary analysis. |
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| Keywords: | guaiacol bromination 5-bromo-2-methoxyphenol deprotection |
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