生物医用纺织肠道支架研究进展

综述结直肠癌的背景,常用的外科治疗方法,以及肠道支架辅助治疗的必要性、安全性、有效性、适应症与并发症等情况;分析现阶段已有的肠道支架类型、材料组成、纺织加工技术,微创手术植入的基本原理、方法、步骤,以及传统肠道支架的不足;阐述新型复合肠道支架的研究现状,并提出未来新型肠道支架的研究方向。结论是开发具有良好的生物相容性、局部可降解、靶向性给药治疗等性能的新型肠道支架非常重要,这也是当前生物医学与纺织科学交叉领域的研究难题和发展方向。

Advances in biomedical textile intestinal stents for treatment of colorectal cancer

The background of colon and rectal cancer ( CRC ) , the commonly used surgical treat-ment methods, as well as the necessity, safety, efficacy, indications and complications, and so on, of the adjuvant therapies, were mainly presented. The types, material composition, and textile processing technology of existing stents, and the basic principle, methods and steps of minimally invasive surgical implants, and the shortcomings and deficiencies of the conventional stents was reviewed. The research status of new composite intestinal stents was de-scribed, and the future research of new intesti-nal stents was proposed. In conclusion, it is important to develop a new type of intestinal stents with a good biocompatibility, biodegradability, targeting medication. This is also the reseach problem and development direction in the crossing field of biomedicine and textile science.