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| 丹皮酚结构改造研究进展 | |
| 引用本文： | 袁金伟,屈凌波,白云亮,屈智博,陈晓岚,石含玉.丹皮酚结构改造研究进展[J].河南工业大学学报(自然科学版),2011,32(3):88-94. |
| 作者姓名： | 袁金伟 屈凌波 白云亮 屈智博 陈晓岚 石含玉 |
| 作者单位： | 1. 河南工业大学,化学化工学院,河南郑州450001 2. 河南工业大学,化学化工学院,河南郑州450001;郑州大学,化学系,河南省化学生物学与有机化学重点实验室,河南郑州450052 3. 郑州大学,化学系,河南省化学生物学与有机化学重点实验室,河南郑州450052 |
| 基金项目： | 国家自然科学基金，河南省科技创新杰出人才基金 |
| 摘 要： | 丹皮酚是传统中药牡丹皮的有效成分,具有广泛的生物活性,如抗菌消炎、镇痛、抗肿瘤和预防心血管系统疾病等.近年来,随着对丹皮酚作用及机制研究的不断拓展和深入,对其结构修饰和改造也开展了大量的工作,合成出一系列的丹皮酚衍生物,对丹皮酚结构改造的研究现状进行了系统的综述. |
| 关 键 词： | 丹皮酚 结构修饰 生物活性 |
RESEARCH PROGRESS ON THE STRUCTURE MODIFICATION OF PAEONOL |
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| YUAN Jin-wei,QU Ling-bo,BAI Yun-liang,QU Zhi-bo,CHEN Xiao-lan,SHI Han-yu.RESEARCH PROGRESS ON THE STRUCTURE MODIFICATION OF PAEONOL[J].Journal of Henan University of Technology Natural Science Edition,2011,32(3):88-94. | |
| Authors: | YUAN Jin-wei QU Ling-bo BAI Yun-liang QU Zhi-bo CHEN Xiao-lan SHI Han-yu |
| Affiliation: | YUAN Jin-wei1,QU Ling-bo1,2,BAI Yun-liang2,QU Zhi-bo2,CHEN Xiao-lan2,SHI Han-yu2 (1.School of Chemistry & Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China,2.Department of Chemistry,Zhengzhou University,Key Laboratory of Chemical Biology and Organic Chemistry,Zhengzhou 450052,China) |
| Abstract: | Paeonol,an effective component of traditional herb Cortex Moutan,has comprehensive pharmacological activities,such as antibacterial,anti-inflammatory,pain-relieving,anticancer and preventing cardiovascular diseases.In recent years,a great amount of work on the structure modification of paeonol was done to synthesize a series of paeonol derivatives as the study on the effect and mechanism of paeonol was increasingly intensively developed.The paper systematically reviewed the research progress on the structur... |
| Keywords: | paeonol structural modification biological activities |
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