| 5-(N-桂皮酰基)氨基水杨酸的合成 |
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| 引用本文： | 胡钟,肖幼安,何黎琴,王效山. 5-(N-桂皮酰基)氨基水杨酸的合成[J]. 安徽化工, 2011, 37(5): 48-49 |
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| 作者姓名： | 胡钟 肖幼安 何黎琴 王效山 |
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| 作者单位： | 安徽中医学院,安徽省现代中药重点实验室,安徽合肥230031;安徽中医学院,安徽省现代中药重点实验室,安徽合肥230031;安徽中医学院,安徽省现代中药重点实验室,安徽合肥230031;安徽中医学院,安徽省现代中药重点实验室,安徽合肥230031 |
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| 摘 要： | 目的：合成5-（N-桂皮酰基）氨基水杨酸。方法：以桂皮酸为原料,经酰氯化后与5-氨基水杨酸成酰胺修饰后合成目标物。结果与结论：合成得到了5-（N-桂皮酰基）氨基水杨酸,目标化合物通过IR、1HNMR和MS等确证,产率为61.8%。
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| 关 键 词： | 桂皮酸 5-氨基水杨酸 5-(N-桂皮酰基)氨基水杨酸 |
Synthesis of 5-(N-cinnamacyl) Aminosalicylic Acid |
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| HU Zhong,XIAO You-an,HE Li-qin,WANG Xiao-shan. Synthesis of 5-(N-cinnamacyl) Aminosalicylic Acid[J]. Anhui Chemical Industry, 2011, 37(5): 48-49 |
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| Authors: | HU Zhong XIAO You-an HE Li-qin WANG Xiao-shan |
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| Affiliation: | HU Zhong,XIAO You-an,HE Li-qin,WANG Xiao-shan(Anhui College of Traditional Chinese Medicine,Anhui Modern Traditional Chinese Medicinal Key Laboratory,Hefei 230031,China) |
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| Abstract: | Objective:Synthesis of 5-(N-cinnamacyl) aminosalicylic acid from cinnamic acid and 5-aminosalicylic acid was reported.Methods:The synthesis involved cinnamic acid acyl chlorination,then reacted with 5-aminosalicylic acid to obtain 5-(N-cinnamacyl) aminosalicylic acid.Results and conclusions:The chemical structure of 5-(N-cinnamacyl) aminosalicylic acid was confirmed by IR,1HNMR and MS.The yield was over 60%. |
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| Keywords: | cinnamic acid(CNN) 5-aminosalicylic acid(5-ASA) 5-(N-cinnamacyl) aminosalicylic acid |
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