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Approach to the Controlled Synthesis of Nucleopeptides I. Nε-(6-Purinoyl-L-Lysine and β-(5-Uracilyl)-Dl-Alanine
Authors:A Vincze  Ch Lachman  S Cohen
Abstract:Nε-(6-purinoyl)-L-lysine has been prepared by acylation of L-lysine copper complex or Nα-carbobenzoxy-L-lysine with 6-trichloromethylpurine followed by the removal of the protecting group. β-(5-uracilyl)-DL-alanine has been prepared by condensation of 5-chloro-methyluracil with diethyl acetamidomalonate, followed by acid hydrolysis.
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