低浓度乙二胺四乙酸对金黄色葡萄球菌生物被膜形成的影响 |
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引用本文: | 郭志华,胡婷婷,单玲玲. 低浓度乙二胺四乙酸对金黄色葡萄球菌生物被膜形成的影响[J]. 食品与发酵工业, 2012, 38(12) |
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作者姓名: | 郭志华 胡婷婷 单玲玲 |
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作者单位: | 宿州学院化学与生命科学学院,安徽宿州,234000 |
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基金项目: | 宿州学院科研平台开放课题,安徽省自然科学基金资助项目,安徽省高等学校优秀青年人才基金项目,自旋电子与纳米材料安徽省重点实验室培育基地开放课题资助 |
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摘 要: | 研究了低浓度乙二胺四乙酸(EDTA)对食源性病原菌金黄色葡萄球菌生物被膜形成的影响。实验结果表明,0.2mmol/L的EDTA可有效抑制金黄色葡萄球菌生物被膜形成;EDTA只能影响金黄色葡萄球菌生物被膜形成的早期阶段;Ba2+不能完全阻断EDTA抑制生物被膜生成,Fe2+、Ca2+、Mg2+可以阻断EDTA抑制生物被膜的效应;即使是高浓度的EDTA也不能影响成熟的细胞被膜数量;EDTA能抑制细胞之间的粘附作用。
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关 键 词: | 乙二胺四乙酸(EDTA) 金黄色葡萄球菌 生物被膜 |
Effect of Low Concentration of EDTA on Biofilm Formation of Staphylococcus aureus |
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Abstract: | The effect of low concentration of EDTA on bio?lm formation of Staphylococcus aureus was studied.The results showed that 0.2 mmol/L EDTA could effectively inhibit bio?lm formation of Staphylococcus aureus.EDTA could only influence the early stages of biofilm formation of Staphylococcus aureus.The inhibition of biofilm with EDTA could not be completely blocked by Ba2+,but it could be blocked by Fe2+,Ca2+,and Mg2+.Even high concentrations of EDTA could not influence the mature biofilm.EDTA could inhibit the adhesion between cells. |
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Keywords: | EDTA Staphylococcus aureus biofilm |
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