1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole |
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| Authors: | Barboiu M Cimpoesu M Guran C Supuran C T |
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| Affiliation: | Research Center for Macromolecular Materials and Membranes Spl. Independentei 206 Bucharest 79611 Romania. |
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| Abstract: | Metal complexes of the title ligand (L) containing Co(II), Ni(II) and Cu(II) were prepared and characterized by elemental analysis, IR, electronic spectroscopy and conductimetry. The new derivatives, possessing the following formulae, CuL(2)(OH)(2), NiL(2)Cl(2), and Co(2)LCl(4)](n) showed in vitro antifungal activity against Aspergillus and Candida spp. |
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