Electrospinning of gelatin and gelatin/poly(l-lactide) blend and its characteristics for wound dressing |
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| Authors: | Shu-Ying Gu Zhi-Mei Wang Jie Ren Chun-Yan Zhang |
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| Affiliation: | 1. Institute of Nano- and Bio-Polymeric Materials, School of Materials Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China;2. Key Laboratory of Advanced Civil Engineering Materials, Ministry of Education, School of Materials Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China |
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| Abstract: | Gelatin nanofibres were electrospun from its aqueous acetic acid solution. Electrospinning parameters, such as concentration of aqueous acetic acid and gelatin solutions, electric field and spinning distance, were examined to investigate the electrospinnability of gelatin solutions and the morphology of gelatin nanofibrous mats. Nanofibrous mats from poly(l-lactide) (PLLA) and gelatin/PLLA solutions were obtained. The electrospun mats showed controlled evaporative water loss, promoted fluid drainage ability, and excellent biocompatibility, and therefore have a potential application as wound dressing. |
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