Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441 |
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| Authors: | Chiara Uboldi Daniele Bonacchi Giada Lorenzi M Iris Hermanns Christine Pohl Giovanni Baldi Ronald E Unger C James Kirkpatrick |
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| Affiliation: | (1) Institute of Pathology – REPAIR Lab, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany;(2) CERICOL – Centro di Ricerche Colorobbia, Via Pietramarina 123, 50059 Firenze, Italy |
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| Abstract: | Background During the last years engineered nanoparticles (NPs) have been extensively used in different technologies and consequently
many questions have arisen about the risk and the impact on human health following exposure to nanoparticles. Nevertheless,
at present knowledge about the cytotoxicity induced by NPs is still largely incomplete. In this context, we have investigated
the cytotoxicity induced by gold nanoparticles (AuNPs), which differed in size and purification grade (presence or absence
of sodium citrate residues on the particle surface) in vitro, in the human alveolar type-II (ATII)-like cell lines A549 and NCIH441. |
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