Injectable and fast resorbable calcium phosphate cement for body-setting bone grafts |
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| Authors: | I Rajzer O Castaño E Engel J A Planell |
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| Affiliation: | (1) Institute for Bioengineering of Catalonia (IBEC), C/Baldiri i Reixach, 4–6, Tower I, 10th floor, 08028 Barcelona, Spain;(2) Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Barcelona, Spain;(3) Department of Polymer Materials, ATH, University of Bielsko-Biala, Institute of Textile Engineering and Polymer Materials, Bielsko-Biała, Poland;(4) Technical University of Catalonia (UPC), Barcelona, Spain; |
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| Abstract: | In this work a calcium phosphate (CPC)/polymer blend was developed with the advantage of being moldable and capable of in
situ setting to form calcium deficient hydroxyapatite under physiological conditions in an aqueous environment at body temperature.
The CPC paste consists in a mix of R cement, glycerol as a liquid phase carrier and a biodegradable hydrogel such as Polyvinyl
alcohol, which acts as a binder. Microstructure and mechanical analysis shows that the CPC blend can be used as an injectable
implant for low loaded applications and fast adsorption requirements. The storage for commercial distribution was also evaluated
and the properties of the materials obtained do not significantly change during storage at −18°C. |
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