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Long-term changes in straylight induced by corneal refractive therapy: A pilot study
Affiliation:1. Departament of Optics II, Copmplutense University of Madrid, Spain;2. Clínica Novovisión, Madrid, Spain;1. Department of Molecular Neurobiology and Neuropathology, National Institute of Neurology, La Rabta, Tunis, Tunisia;2. National Institute on Aging, Porter Neuroscience Research Center, National Institutes of Health, Building 35, Room 1A1010, Bethesda, MD 20892, USA;3. Laboratory of Biochemistry, Rabta Hospital, Tunis, Tunisia;1. Department of Optics II (Optometry and Vision), Faculty of Optics and Optometry, Universidad Complutense de Madrid, Madrid, Spain;2. Department of Biochemistry and Molecular Biology IV, Faculty of Optics and Optometry, Universidad Complutense de Madrid, Madrid, Spain;1. Erzurum Regional Training and Research Hospital, Department of Ophthalmology, Erzurum, Turkey;2. Beyoglu Eye Research and Education Hospital, Istanbul, Turkey;3. Kelkit State Hospital, Department of Ophthalmology, Gümü?hane, Turkey;4. ?ehit Kamil State Hospital, Department of Ophthalmology, Gaziantep, Turkey;5. Ergani State Hospital, Department of Ophthalmology, Diyarbak?r, Turkey
Abstract:PurposeTo assess long-term intraocular straylight changes induced by corneal refractive therapy (CRT) and to determine whether these changes persist after cessation of CRT lens wear.MethodsA single-center, prospective, longitudinal study was performed in 22 subjects (group 1) undergoing overnight corneal refractive therapy for 1 year. Ten right eyes of 10 subjects (group 2) with emmetropia served as controls. In each subject, high contrast visual acuity (HCVA), manifest refraction and intraocular straylight were determined at several time points during treatment and 1 month after discontinuing treatment. Straylight was measured using the van den Berg straylight meter (third generation). EDTRS charts (logMAR units) were used to assess HCVA. For both groups, only data for the right eyes were analyzed.ResultsStraylight (mean ± standard deviation) significantly fell from baseline (0.98 ± 0.13) to values recorded after 1 month (0.88 ± 0.13, p = 0.011), 3 months (0.88 ± 0.13, p = 0.004), 6 months (0.88 ± 0.13, p = 0.000) and 12 months (0.76 ± 0.12, p = 0.003) of treatment. One month after discontinuing CRT lens wear, straylight was still significantly lower than baseline (0.89 ± 0.13, p = 0.003). No correlations were observed between intraocular straylight and HCVA.ConclusionsGood refractive outcomes and reductions in straylight were observed in response to corneal refractive therapy for myopia. The reduction in straylight observed after discontinuing CRT warrents further investigation.
Keywords:Cornea  Intraocular straylight  Corneal refractive therapy
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