Advancements and Challenges in Multidomain Multicargo Delivery Vehicles |
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| Authors: | Eugenia Pugliese João Q Coentro Dimitrios I Zeugolis |
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| Affiliation: | 1. Regenerative, Modular and Developmental Engineering Laboratory (REMODEL), Biomedical Sciences Building, National University of Ireland Galway (NUI Galway), Ireland;2. Science Foundation Ireland (SFI), Centre for Research in Medical Devices (CúRAM), Biomedical Sciences Building, National University of Ireland Galway (NUI Galway), Ireland |
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| Abstract: | Reparative and regenerative processes are well‐orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer‐by‐layer, composite, self‐assembly, and core–shell technologies are discussed for the development of multidomain/multicargo delivery vehicles. |
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| Keywords: | coaxial electrospinning/electrospraying dendrimers/polymersomes/micelles/liposomes multicompartment biomaterials multidrug/gene/cell delivery |
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