| 利用磷酸化质谱的预处理提高磷酸化肽的鉴定 |
| |
| 引用本文： | 孙瑞祥,袁作飞,迟浩,王文平,付岩,贺思敏. 利用磷酸化质谱的预处理提高磷酸化肽的鉴定[J]. 质谱学报, 2010, 31(Z1): 39-40 |
| |
| 作者姓名： | 孙瑞祥 袁作飞 迟浩 王文平 付岩 贺思敏 |
| |
| 作者单位： | 中国科学院计算技术研究所智能信息处理重点实验室，北京 100190 |
| |
| 摘 要： |
|
Preprocessing of Phosphopeptide Mass Spectra to Improve Their Identifications |
| |
| SUNRui-xiang,YUANZuo-fei,CHIHao,WANGWen-ping,FUYan,HESi-min. Preprocessing of Phosphopeptide Mass Spectra to Improve Their Identifications[J]. Journal of Chinese Mass Spectrometry Society, 2010, 31(Z1): 39-40 |
| |
| Authors: | SUNRui-xiang YUANZuo-fei CHIHao WANGWen-ping FUYan HESi-min |
| |
| Affiliation: | Key Lab for Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China |
| |
| Abstract: | Post-acquisition mass spectral processing can significantly enhance the identification rate from both MS and MS/MS spectra. In this study we focused on how to improve phosphopeptide identification by utilizing the neutral-loss patterns hidden in a large set of tandem mass spectra. We also calibrated the precursor mass to further improve their mass measurement accuracy. The experiments on iPRG2010 data set show that these two types of spectral preprocessing can greatly benefit the phosphopeptide identification using both our developed search engine pFind and the commercial software Mascot. |
| |
| Keywords: | phosphorylation tandemmassspectrometry neutral-loss peptideidentification dataanalysis |
|
| 点击此处可从《质谱学报》浏览原始摘要信息 |
|
点击此处可从《质谱学报》下载全文 |
|
