Silicon-substituted hydroxyapatite composite coating by using vacuum-plasma spraying and its interaction with human serum albumin |
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Authors: | Feng-juan Xiao Lei Peng Ying Zhang Li-jiang Yun |
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Affiliation: | (1) Department of Material Science and Engineering, Shjiazhuang Railway Institute, No.17 North 2nd-Ring East Road, Shijiazhuang, 050043, Hebei Province, China |
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Abstract: | The incorporation of silicon can improve the bioactivity of hydroxyapatite (HA). Silicon-substituted HA (Ca10(PO4)6−x
(SiO4)
x
(OH)2−x
, Si-HA) composite coatings on a bioactive titanium substrate were prepared by using a vacuum-plasma spraying method. The
surface structure was characterized by using XRD, SEM, XRF, EDS and FTIR. The bond strength of the coating was investigated
and XRD patterns showed that Ti/Si-HA coatings were similar to patterns seen for HA. The only different XRD pattern was a
slight trend toward a smaller angle direction with an increase in the molar ratio of silicon. FTIR spectra showed that the
most notable effect of silicon substitution was that –OH group decreased as the silicon content increased. XRD and EDS elemental
analysis indicated that the content of silicon in the coating was consistent with the silicon-substituted hydroxyapatite used
in spraying. A bioactive TiO2 coating was formed on an etched surface of Ti, and the etching might improve the bond strength of the coatings. The interaction
of the Ti/Si-HA coating with human serum albumin (HSA) was much greater than that of the Ti/HA coating. This might suggest
that the incorporation of silicon in HA can lead to significant improvements in the bioactive performance of HA. |
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Keywords: | |
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