Nontoxic pH-sensitive silver nanocomposite hydrogels for potential wound healing applications |
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| Authors: | S Sudarsan M S Selvi G Chitra S Sakthivel D S Franklin |
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| Affiliation: | 1. Department of Chemistry, C. Abdul Hakeem College of Engineering and Technology , Melvisharam, India;2. PG &3. Research Department of Chemistry, Muthurangam Government Arts College(Autonomous) , Vellore, India;4. Department of Chemistry, Bangalore College of Engineering and Technology , Bangalore, India |
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| Abstract: | ABSTRACT Silver nanocomposite (SNC) containing pH sensitivity with fascinating attention may be recommended for extensive utilization in eco-friendly nanomaterial applications. In the present investigation, a strategy to fabricate new biodegradable and biocompatible hydrogels based on sodium alginate/ethylene glycol/acrylic acid functionalized with silver nanocomposites, which were synthesized by a facile greener method. The swelling profile is enhanced the stimuli responsive behavior of nanocomposite hydrogels. The synthesized nanocomposite hydrogels has showed a significant pH-sensitive behavior which induced the degradation profile, cell viability, and antimicrobial activity. Hence, this kind of biomaterials has been utilized for nontoxic, degradable wound healing dressing. |
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| Keywords: | Swelling sodium alginate nanocomposite degradation wound healing |
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