Comparative hypocholesterolemic effects of six vegetable oils in cholesterol-fed rat |
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Authors: | Michihiro Fukushima Shiori Akiba Masuo Nakano |
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Affiliation: | (1) Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, 080 Obihiro, Hokkaido, Japan |
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Abstract: | The hypocholesterolemic efficacies of various polyunsaturated fatty acids were compared in rats given cholesterol-enriched
diets.Oenothera biennis Linn oil (OBLO, linoleic +γ-linolenic), sunflower oil (linoleic), palm oil (PLO, oleic+linoleic), soybean oil (linoleic+α-linolenic),
high-oleic safflower oil (oleic+linoleic), or mixed oil (linoleic+α-linolenic) was added to the diet at 200 g/kg (20% groups).
OBLO was also added at 100 g/kg diet (10% group). The serum total and very low density lipoprotein+intermediate lipoprotein+low
density lipoprotein cholesterol concentrations of the 10 and 20% OBLO groups were consistently lower than those in the other
groups. The liver cholesterol concentration in the PLO group was lower in all groups. The liver cholesterol concentrations
in the 10 and 20% OBLO groups were also lower than in the other groups. There were no significant differences in the fecal
neutral sterol and bile acid extraction among groups. |
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