The use of randomized clinical trials in rehabilitation psychology.

Purpose: This article provides rehabilitation psychology researchers and clinicians with a tutorial approach to randomized clinical trials (RCTs), their basic assumptions and requirements, and a discussion of their potential applications and limitations to their use in rehabilitation and, more specifically, in rehabilitation psychology. Research Method/Design: The authors begin by reviewing a brief history and development of RCTs, definitions and considerations for clinical trials, and ethical issues. An overview of methodological issues related to designing trials including randomization and blinding, subject selection, and protocol development is provided. Results: The authors emphasize the need to establish clear and concise study objectives and to explicitly define interventions and expected outcomes. Conclusions/Implications: A summary is provided of the main points made by those supporting the use of RCTs versus those who highlight their limitations. Taking these into account, recommendations are made regarding the use of RCTs in addressing relevant needs in clinical practice and research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)