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A Pharmacokinetic and Metabolism Study of the TRPC6 Inhibitor SH045 in Mice by LC-MS/MS |
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| Authors: | Xiao-Ning Chai,Friedrich-Alexander Ludwig,Anne Mü glitz,Yuanyuan Gong,Michael Schaefer,Ralf Regenthal,Ute Krü gel |
| Affiliation: | 1.Rudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, 04107 Leipzig, Germany; (X.-N.C.); (A.M.); (Y.G.); (M.S.);2.Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany;3.Clinical Pharmacology, Rudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, 04107 Leipzig, Germany; |
| Abstract: | |
| Keywords: | cytochrome P450 enzyme kidney larixol LC-MS/MS lung mice microsomes pharmacokinetics toxicity SH045 TRPC6 inhibitor |