| 2,5-二甲基-3,4-二氢-4-氧代喹唑啉的合成研究 |
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| 引用本文： | 康从民,周海燕.2,5-二甲基-3,4-二氢-4-氧代喹唑啉的合成研究[J].化学与生物工程,2012(6):24-25. |
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| 作者姓名： | 康从民 周海燕 |
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| 作者单位： | 青岛科技大学化工学院 |
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| 基金项目： | 国家自然科学基金资助项目(21072111);山东省自然科学基金资助项目(ZR2011BM015) |
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| 摘 要： | 对2,5-二甲基-3,4-二氢-4-氧代喹唑啉的合成进行了研究。以间甲基苯胺为原料经3步反应制得2-氨基-6-甲基苯甲酸,再环化生成2,5-二甲基-3,4-二氢-4-氧代喹唑啉。中间体及标题化合物结构经1 HNMR确证。
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| 关 键 词： | 2 5-二甲基-3 4-二氢-4-氧代喹唑啉 间甲基苯胺 合成工艺 |
Study on Synthesis of 2,5-Dimethyl-3,4-dihydro-4-oxo-quinazoline |
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| KANG Cong-ming,ZHOU Hai-yan.Study on Synthesis of 2,5-Dimethyl-3,4-dihydro-4-oxo-quinazoline[J].Chemistry & Bioengineering,2012(6):24-25. |
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| Authors: | KANG Cong-ming ZHOU Hai-yan |
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| Affiliation: | (College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China) |
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| Abstract: | Synthesis of 2,5-dimethyl-3,4-dihydro-4-oxo-quinazoline was studied in the paper.2-Amino-6-methyl-benzoic acid was obtained via three steps with m-toluidine as starting material.Then,2,5-dimethyl-3,4-dihydro-4-oxo-quinazoline was prepared by cyclization.The structures of intermediates and object compound were characterized by 1HNMR. |
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| Keywords: | 2 5-dimethyl-3 4-dihydro-4-oxo-quinazoline m-toluidine synthetic technique |
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