Patulin in apple-based foods: occurrence and safety evaluation |
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Authors: | Barbara Beretta Antonella Gaiaschi Corrado L Galli Patrizia Restani |
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Affiliation: |
a Laboratory of Toxicology, Institute of Pharmacological Sciences, University of Milan, via Balzaretti 9, 20133 Milan, Italy. |
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Abstract: | Patulin is a mycotoxin produced by certain species of Penicillium and Aspergillus, often detectable in mouldy fruits and their derivatives. On the basis of a PMTDI of 0.4 mu g/kg bw, limit values of 50 mu g/kg or 50 mu g/l of patulin have been set in fruit derivatives. To estimate the quantity of patulin that can be taken in with the diet, we analysed by HPL C samples of apples and apple derivatives which are most likely to be contaminated with patulin. In apple juices and in homogenized babyfoods, the mycotoxin concentration was always below the established limits, while in some samples of juice with pulp the mycotoxin content exceeded the safe levels. In rotten apples, not only was the amount of patulin extraordinarily high in the rotten area, but the mycotoxin had also spread to the part unaffected by mould. The data presented in this study indicate that the intake of patulin with apple derivatives is usually below the tolerable level of 0.4 mu g/kg bw/day, but since the patulin content in apples can vary considerably, the quality of fruits used in the production of apple derivatives should be strictly controlled in order not to exceed the safe limits. |
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Keywords: | Patulin Mycotoxins Apple-DERIVATIVES |
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