植物代谢组学及其在烟草上的应用进展

作为系统生物学的一个重要分支,代谢组学是一门研究生物体系受内外环境扰动后(基因的改变或环境的变化),其产生的小分子代谢物变化的科学。代谢组学已被广泛应用于天然药物开发、植物学、微生物学和食品安全等研究领域。本文对代谢组学的形成与发展、植物代谢组学研究方法及其在烟草中的应用进行了综述,并对植物代谢组学的发展及其在烟草中的应用进行了展望。认为代谢组学将在烟草基因功能解析、揭示代谢网络调控机理和提高烟草品质等生物技术应用方面发挥不可替代的作用。 

Plant metabolomics and its application in tobacco

As one important platform of systems biology, metabolomics focuses on changes of low molecule weight metabolites in a biological system which were imposed by perturbations, including genetic or environmental factors. It has been widely used in different research fields, i.e. natural medicines development, botany, microbiology, and food safety. This paper reviewed the formation and development, research methods and its application in tobacco. The prospect of its further development and application were explored. Metabolomics will play a significant role in functional annotation of tobacco genome, revelation the mechanism of metabolic regulatory networks, and improvement of tobacco quality.