| Single-Ion Microbeam for Applications in Radiobiology： State of the Art |
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| 引用本文： | 胡智文 吴李君 余增亮. Single-Ion Microbeam for Applications in Radiobiology： State of the Art[J]. 等离子体科学和技术, 2005, 7(2): 2789-2796 |
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| 作者姓名： | 胡智文 吴李君 余增亮 |
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| 作者单位： | KeyLaboratoryofIonBeamBioengineering,InstituteofPlasmaPhysics,ChineseAcademyofSciences,Hefei230031,China |
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| 基金项目： | The project supported by the National Major Technologies R & D Program of China during the 10th Five-Year Plan Period (No.2001BA302B)and the National Science Fund for Distinguished Young Scholars (No. 10225526) |
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| 摘 要： | Single-Ion Microbeam (SIM) is uniquely capable of precisely delivering a predefined number of charged particles (precise doses of radiation) to individual cells or sub-cellular targets in situ. Since the early 1990‘s, there has been an ever-increasing interest in developing and applying the SIM technique to problems in radiobiology for studies of cell and tissue damaged by ionizing radiations. Potential applications for SIM in radiobiology continues to grow and have been diversified. There are currently more than 14 SIM facilities worldwide, and they have been in a constant state of evolution. This paper reviews the current state of SIM research worldwide and the related pivotal technological developments in the fields of both biophysics and radiobiology. Representative applications and the perspective of SIM are also introduced and discussed.
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| 关 键 词： | 简单离子微光束 放射生物学 带电细胞 研究方向 |
Single-Ion Microbeam for Applications in Radiobiology: State of the Art |
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| Hu Zhiwen,Wu Lijun,Yu Zengliang. Single-Ion Microbeam for Applications in Radiobiology: State of the Art[J]. Plasma Science & Technology, 2005, 7(2): 2789-2796 |
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| Authors: | Hu Zhiwen Wu Lijun Yu Zengliang |
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| Abstract: | Single-Ion Microbeam (SIM) is uniquely capable of precisely delivering a predefined number of charged particles (precise doses of radiation) to individual cells or sub-cellular targets in situ. Since the early 1990's, there has been an ever-increasing interest in developing and applying the SIM technique to problems in radiobiology for studies of cell and tissue damaged by ionizing radiations. Potential applications for SIM in radiobiology continues to grow and have been diversified. There are currently more than 14 SIM facilities worldwide, and they have been in a constant state of evolution. This paper reviews the current state of SIM research worldwide and the related pivotal technological developments in the fields of both biophysics and radiobiology. Representative applications and the perspective of SIM are also introduced and discussed. |
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| Keywords: | single-ion microbeam radiobiology |
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