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L-阿拉伯糖对营养性肥胖大鼠的减肥作用研究
引用本文:吴建璋,杨子明,颜小捷,刘金磊,卢凤来,李典鹏. L-阿拉伯糖对营养性肥胖大鼠的减肥作用研究[J]. 食品研究与开发, 2012, 33(5): 181-183
作者姓名:吴建璋  杨子明  颜小捷  刘金磊  卢凤来  李典鹏
作者单位:1. 广西植物功能物质研究与利用重点实验室广西植物研究所,广西桂林,541006
2. 广西师范大学,广西桂林,541004
基金项目:科技攻关与新产品试剂(合同编号:桂科攻1140001-36)
摘    要:通过高脂饮食诱导建立营养性肥胖大鼠模型,研究L-阿拉伯糖(LA)对其的减肥作用。通过高脂饮食诱导60 d建立肥胖模型,灌胃给予治疗80 d,检测体重、血糖、肥胖指数(Lee’s指数)、脂肪湿重、脂肪系数和肝指数的变化情况。结果发现,灌胃治疗80 d后,与肥胖模型组相比,L-阿拉伯糖给药组能明显减轻肥胖大鼠体重,明显抑制血糖升高,明显降低Lee’s指数、脂肪湿重、脂肪系数和肝指数。L-阿拉伯糖对营养性肥胖大鼠有较好的减肥和降血糖效果。

关 键 词:营养性肥胖  L-阿拉伯糖  减肥  高脂饮食

Weight-reducing Effect of L-arabinose in Diet-induced Obese Rats
WU Jian-zhang , YANG Zi-ming , YAN Xiao-jie , LIU Jin-lei , LU Feng-lai , LI Dian-peng. Weight-reducing Effect of L-arabinose in Diet-induced Obese Rats[J]. Food Research and Developent, 2012, 33(5): 181-183
Authors:WU Jian-zhang    YANG Zi-ming    YAN Xiao-jie    LIU Jin-lei    LU Feng-lai    LI Dian-peng
Affiliation:1,(1.Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization,Guangxi Institute of Botany,Chinese Academy of Sciences,Guilin 541006,Guangxi,China;2.Guangxi Normal University,Guilin 541004,Guangxi,China)
Abstract:To study the effect of high-fat diet on inducing obesity rats,and the effect of reducing fat of L-arabinose in these rats.The experimental rats were given high-fat diet for 60 days to setup the model,drugs were administered intragastrically to obese rats for 80 days.Then body weight,blood sugar,Lee’s index,fat tissue weight,fat tissue index and liver index were detected.Results showed that,for 80 days treatment,in comparing with the model group,the levels of body weight,blood sugar,Lee’s index,fat tissue weight,fat tissue index and liver index in rats given with L-arabinose were decreased significantly.The L-arabinose could reduce fat and blood sugar in diet-inducde obese rats.
Keywords:diet-induced obesity  L-arabinose  weight reduction  high-fat diet
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