Isolation and identification of Mycobacterium cultures antagonistic to phytopathogenic microflora |
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Authors: | NV Kozlovskaia IO Obgol''tseva EP Iakovleva |
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Affiliation: | Gromashevsky Research Institute of Epidemiology and Infectious Diseases, Kiev, Ukraine. |
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Abstract: | The immunosuppressive activity of extracellular and water-phenol lipopolysaccharides (LPS) of S.minnesota in S- and R-forms, as well as their gel-filtration, polysaccharide and lipid fractions, was studied in mouse experiments on the model of delayed type hypersensitivity (DTH). The study revealed that the extracellular LPS of S-form S.minnesota was capable of suppressing DTH with lipid A playing the decisive role in this immunosuppressive activity. The extracellular LPS of Reform S.minnesota did not possess the capacity for immunosuppression, but acquired it after redox treatment. |
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