| 滁菊总黄酮对糖尿病大鼠血液流变学的影响 |
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| 引用本文： | 滁菊总黄酮对糖尿病大鼠血液流变学的影响[J]. 食品工业科技, 2013, (15): 351-354. DOI: 10.13386/j.issn1002-0306.2013.15.030 |
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| 作者姓名： | 俞浩 周金星 马世堂 张孝林 杨剑婷 |
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| 作者单位： | 安徽科技学院食品药品学院,安徽蚌埠,233100 |
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| 基金项目： | 安徽省青年科学基金项目，安徽科技学院稳定人才项目 |
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| 摘 要： | 目的:观察滁菊总黄酮对糖尿病大鼠血液流变学的影响。方法:采用尾静脉注射链脲佐菌素(STZ)的方法建立糖尿病大鼠模型,观察滁菊总黄酮对糖尿病大鼠凝血时间,体外血栓长度及干、湿重,全血和血浆粘度,红细胞压积和红细胞沉降速率,以及血清一氧化氮(NO)含量的影响。结果:滁菊总黄酮能显著延长糖尿病大鼠凝血时间,降低体外血栓长度和干、湿重,降低红细胞压积,减慢红细胞沉降速率,升高血清NO含量。结论:滁菊总黄酮能够改善糖尿病大鼠血液流变学异常。
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| 关 键 词： | 滁菊总黄酮 糖尿病大鼠 血液流变学 |
| 收稿时间： | 2012-12-27 |
Effects of total flavonoids from chuju on hemorheology in diabetic rats |
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| Effects of total flavonoids from chuju on hemorheology in diabetic rats[J]. Science and Technology of Food Industry, 2013, (15): 351-354. DOI: 10.13386/j.issn1002-0306.2013.15.030 |
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| Abstract: | Objective: To observe the effect of total flavonoids from chuju on hemorheology in diabetic rats.Methods: The diabetic rat model was induced by vena caudalis injecting streptozotocin.The clotting time was determined, the length, dry and wet weight of thromb, viscosity of whole blood and plasma, erythrocyte sedimentation rate and hematocrit were measured, and the concentration of NO in serum was also determined. Results: Total flavonoids from chuju could significantly prolong the clotting time, reduce the length, dry and wet weight of thromb, viscosity of whole blood and plasma, erythrocyte sedimentation rate and hematocrit, decrease the concentration of NO in serum.Conclusion: Total flavonoids from chuju could improve hemorheology abnormality of diabetic rats. |
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| Keywords: | total flavonoids from chuju diabetic rats hemoreheology |
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