Shear strength of cancellous bone after osteotomy fixed with absorbable self-reinforced polyglycolic acid and poly-L-lactic acid rods |
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| Authors: | Manninen M. J. Päivärinta U. Pätiälä H. Rokkanen P. Taurio R. Tamminmäki M. Törmälä P. |
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| Affiliation: | (1) Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland;(2) Biomaterials Laboratory, Tampere University of Technology, Tampere, Finland |
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| Abstract: | The right distal femur of 42 adult rabbits was osteotomized and fixed with two 1.5 mm in diameter metallic Kirschner wires, self-reinforced polyglycolic acid (SR-PGA, Biofix®), or self-reinforced poly-L-lactic acid (SR-PLLA) rods. Follow-up times were 6 and 12 weeks. The shear strength of 30 pairs of femora was investigated. The strength of osteotomized bones was compared with the non-osteotomized controls. After six weeks the operated femora had reached 70, 69 and 71% shear strength in metallic, SR-PGA and SR-PLLA groups, respectively. After 12 weeks the shear strength values were 75, 79 and 73%, respectively. There was no statistically significant difference in shear strength values between the groups. Twelve pairs of femora were studied with microradiographic, oxytetracyclic fluorescence, and histologic methods. Normal bone healing was seen in these samples. Metallic and SR-PLLA implants caused slight foreign-body reaction with giant cells and SR-PGA rods led to slight infiltration of macrophages and foam cells. |
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