| 乙肝疫苗苦参素拉米夫定联合治疗慢性乙型肝炎的临床研究 |
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| 作者单位： | 河南省新乡市传染病医院肝病科，河南第一荣康医院放疗科 |
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| 摘 要： | 目的探讨乙肝疫苗苦参素拉米夫定联合治疗慢性乙型肝炎的临床疗效。方法随机选择62例慢性乙型肝炎患者分为治疗组31例,苦参素0.2tidpo。疗程7～9个月,乙肝疫苗60ug,每15天1次,皮下注射,疗程12个月,拉米夫定0.1qdpo.疗程12个月。对照组31例单用拉米夫定0.1qdpo。疗程12个月。疗程中定期检测血常规、谷丙转氨酶(ALT)、HBeAg、抗-HBe、HBV、DNA。结果全部患者完成1年治疗。治疗组ALT复常率,HBeAg/抗-HBe血清转换率、HBVDNA阴转率明显高于对照组(分别为80.6%和51.6%,P<0.05;45.2%和19.4%,P<0.05;77.4%和51.6%,P<0.05)。结论乙肝疫苗、苦参素、拉米夫定联合治疗慢性乙型肝炎疗效优于单用拉米夫定。
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| 关 键 词： | 乙型肝炎 肝炎病毒 苦参素 乙肝疫苗 拉米夫定 临床疗效 |
Clinical Study on Marine Combined with Lamivudine and Hepatitis B Vaccine in the Treatment of Chronic Hepatitis B |
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| JIA Qiulong ZHAO Zhifeng HOU Liangbao .Xinxiang City,Henan Province Infectious Disease Hospital Branch. Clinical Study on Marine Combined with Lamivudine and Hepatitis B Vaccine in the Treatment of Chronic Hepatitis B[J]. Friend of Chemical Industry, 2008, 0(32) |
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| Authors: | JIA Qiulong ZHAO Zhifeng HOU Liangbao .Xinxiang City Henan Province Infectious Disease Hospital Branch |
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| Affiliation: | JIA Qiulong ZHAO Zhifeng HOU Liangbao 1.Xinxiang City,Henan Province Infectious Disease Hospital Branch, 2.First Hospital of Henan Rongkang Radiotherapy Branch,Xinxiang 453003,China |
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| Abstract: | |
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| Keywords: | Hepatitis B Hepatitis B virus Marine Hepatitis B vaccine Lamivudine Clinical therapeutic effect |
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