The reaction of active methylene compounds with carbon disulfide in the presence of arylidenemalononitriles: synthesis of 6-amino-2-(4,4-dimethyl/dihydro-2,6-dioxocyclohexylidene)-4-aryl-4H-1,3-dithiine-5-carbonitrile derivatives |
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| Authors: | Hossein Mehrabi Zeinab Esfandiarpour Tayebeh Davodian |
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| Affiliation: | Department of Chemistry, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran |
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| Abstract: | An efficient and simple method for the synthesis of novel ketene dithioacetals via a one-pot three-component reaction of 5,5-dimethylcyclohexan-1,3-dion or 1,3-cyclohexandion with carbon disulfide in the presence of arylidenemalononitriles is reported. The effects of different bases have been investigated and triethylamine can provide products in good to excellent yields at room temperature. The structures of all the synthesized compounds were established from advanced spectroscopic data. |
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| Keywords: | Ketene dithioacetals carbon disulfide arylidenemalononitriles three-component reaction active methylene compounds |
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