静滴藻酸双酯钠治疗冠心病的疗效观察

目的 观察静滴藻酸双酯钠(PSS)治疗32例冠心病患者的疗效。方法 PSS注射液200mg加入10%葡萄糖500ml中静滴,每日1次,14d为疗效;对照组为复方丹参注射液16ml加入10%葡萄糖500ml中静滴,每日1次,14d为1疗程。结果 PSS对心绞痛疗效和复方丹参相近,对心电图、心率、血压、血脂、血流变和心功能的改善均明显优于复方丹参组。结论 PSS对冠心病患者具有明确的疗效。

Therapeutic effects of polysaccharide sulfate intravenous injections in treatment of coronary heart disease

Aim To observe the therapeutic effects of polysaccharide sulfate. Methods Thirty - two patients with coronary heart disease ( M20, F12; age 58±10a) were treated with polysaccharide sulfate 200mg in 10% glucose solution 500ml, iv, drip, qd,for 14d as a courae. For the control group, 16 patients with coronary heart disease (M11, F5; age56±9a) were treated with injection of compound salvia miltiorrhiza 16ml in 10% glucose solution iv, drip, qd, for 14d. Results The efficacy for angina in the polysaccharide sulfate group was similar to that in the compound salvia miltiorrhiza group (90% to 88%), but the EKG, heart rate, pressure blood, blood fat, blood rheology and cardiac function were more significantly improved in the polysaccharide sulfate group than those in the compound salvia miltiorrhiza group(P<0.05). Conclusion Polysaccharide sulfate could have a good effect on the treatment of coronary heart disease.