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C60 and C60-arginine aqueous solutions: In vitro toxicity and structural study |
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| Authors: | Alina A. Tomchuk Nadezhda N. Shershakova Sergey M. Andreev Evgeniy A. Turetskiy Oleksandr I. Ivankov Olena A. Kyzyma |
| Affiliation: | 1. Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Dubna, Russia;2. a.a.tomchuk@gmail.com;4. NRC Institute of Immunology FMBA of Russia, Moscow, Russia;5. I.M. Sechenov First Moscow State Medical University, Moscow, Russia;6. Moscow Institute of Physics and Technology, Dolgoprudny, Russia;7. Faculty of Physics, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine |
| Abstract: | AbstractSmall-angle X-ray and neutron scattering was applied for the structural characterization of aggregates in water dispersions of fullerene C60 prepared by dialysis method and its conjugate with amino acid arginine. Two compounds are also compared with respect to their toxic properties. Experiments on the cytotoxicity of these systems on the A549, HepG2 and HeLa cells showed no toxic effects of the dispersions. |
| Keywords: | C60 fullerene arginine amino acid small-angle neutron scattering small-angle X-ray scattering cytotoxicity |