| 甘薯多糖的抗肿瘤研究 |
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| 引用本文： | 刘主,刘国凌,朱必凤,高建林,彭凌.甘薯多糖的抗肿瘤研究[J].食品研究与开发,2006,27(8):28-31. |
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| 作者姓名： | 刘主 刘国凌 朱必凤 高建林 彭凌 |
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| 作者单位： | 韶关学院英东生物工程学院,广东,韶关,512005 |
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| 摘 要： | 采用水提醇沉法从“广薯98”中提取甘薯粗多糖,通过灌胃给药,研究了甘薯多糖对荷瘤小鼠(H22)的抑瘤率、存活期和脾脏指数、胸腺指数、腹腔巨噬细胞活性的影响。其研究结果显示:甘薯多糖对H22实体瘤小鼠具有明显的抑瘤作用(P<0.05),对H22腹水瘤小鼠具有明显的延长存活期作用(P<0.05);甘薯多糖能明显增加H22实体瘤小鼠的脾脏指数、胸腺指数(P<0.05或P<0.01),能明显增强H22实体瘤小鼠的腹腔巨噬细胞活性(P<0.01)。表明甘薯多糖对H22荷瘤小鼠具有明显的抗肿瘤作用。
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| 关 键 词： | 甘薯 多糖 免疫调节 抗肿瘤 |
| 收稿时间： | 2006-04-01 |
| 修稿时间： | 2006年4月1日 |
THE EXPERIMENTAL STUDY OF SWEET POTATO POLYSACCHARIDE ON ANTITUMOR |
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| LIU Zhu,LIU Guo-ling,ZHU Bi-feng,GAO Jian-lin,PENG Ling.THE EXPERIMENTAL STUDY OF SWEET POTATO POLYSACCHARIDE ON ANTITUMOR[J].Food Research and Developent,2006,27(8):28-31. |
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| Authors: | LIU Zhu LIU Guo-ling ZHU Bi-feng GAO Jian-lin PENG Ling |
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| Affiliation: | Yingdong College of Bioengineering, Shaoguan University, Shaoguan 512005, Guangdong, China |
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| Abstract: | Sweet potato polysaccharide(SPPS)was obtained from the cultivar GuangDong 98 by water extraction and alcohol precipitation. The Kunming mice with H22 tumor were given SPPS by intragastrical injection (i.g.) and studied the inhibiting rate of tumor growth, life prolongation rate, spleen index, thymus index and the activity on macrophage of celiac plexus. The results indicated that SPPS could significantly inhibit the tumor growth(P<0.05) in H22 entity-tumor mice and could significantly prolong life of H22 bearing-tumor mice(P<0.05). SPPS could notably enhanced the spleen index (P<0.05 or P<0.01), the thymus index(P<0.05 or P<0.01) and the activity on macrophage of celiac plexus (P<0.01) in H22 entity-tumor mice. SPPS has anti-tumor function in H22 tumor mice. |
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| Keywords: | sweet potato polysaccharide immunoregulation anti-tumor |
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