| 激光爆破脂质体微泡对视网膜母细胞瘤细胞增殖影响 |
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| 引用本文： | 周宇,周希瑗. 激光爆破脂质体微泡对视网膜母细胞瘤细胞增殖影响[J]. 激光杂志, 2009, 30(1) |
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| 作者姓名： | 周宇 周希瑗 |
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| 作者单位： | 重庆医科大学第二附属医院眼科,重庆,400010;重庆医科大学第二附属医院眼科,重庆,400010 |
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| 摘 要： | 目的:首次探讨激光爆破脂质体微泡造影剂的可行性,并研究其对视网膜母细胞瘤细胞增殖的影响.方法:利用激光在液体中的光声效应,采用Nd-YAG激光.将激光聚焦于脂质体微泡,按照不同的能量参数分组照射,通过DFY-Ⅱ型超声定量分析诊断仪检测微泡爆破率;台盼蓝染色及MTT法研究其对视网膜母细胞瘤细胞增殖影响.结果:激光可成功爆破微泡,不同单脉冲能量(5mJ、10mJ、15mJ)、照射总能量(125mJ、250mJ、500rnJ、750mJ)之间相比有统计学意义(P<0.05);不同激光微泡参数对视网膜母细胞瘤细胞增殖影响亦具统计学意义(P<0.05);结论:Nd:YAG激光能够成功爆破脂质体微泡,在合适的参数下,对视网膜母细胞瘤细胞增殖无明显影响.
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| 关 键 词： | 激光 光声效应 微泡造影剂 超声 Rb细胞 |
Influence to retinoblastoma cell proliferation of using laser to dynamite liposome microbubble contrast medium |
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| ZHOU Yu,ZHOU Xi-yuan. Influence to retinoblastoma cell proliferation of using laser to dynamite liposome microbubble contrast medium[J]. Laser Journal, 2009, 30(1) |
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| Authors: | ZHOU Yu ZHOU Xi-yuan |
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| Affiliation: | Department of Ophthalmology;the Second Affiliated Hospital of Chongqing University of Medical Science;Chongqing 400010;China |
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| Abstract: | Objective:To investigated the feasibility of using laser to dynamite liposome microbubble contrast medium and the influence to retinoblastoma cell proliferation at the first time.Methods:After the preliminary test,we chosen the Nd-YAG laser.The laser light focused on liposome microbubble contrast medium,cells suspl and liposome microbubbje contrast medium/cells suspl,the energy of the light were different in each group.The feasibility of using laser to dynamite liposome microbubble were evaluated by the dyn... |
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| Keywords: | laser light-sound effect microbubble contrast medium ultrasound retinoblastoma cell. |
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