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Multiple factors affect 3‐year survival of patients on chronic hemodialysis
Authors:Sugahara S.  Kanno Y.  Moriwaki K.  Ikeda N.  Takane H.  Kotaki S.  Aoki H.  Ooshima J.  Suzuki H.
Affiliation:A.N. Syzganov's Scientific Center of Surgery, Almaty, Kazakhstan.
Abstract:One of the basic symptoms of a terminal stage chronic renal insufficiency is anemia. From everything, used methods of correction of an anemia, it is considered the most effective application of preparations recombinant human erythropoietin (r‐Hu EPO). Since 1994 in the Scientific Centre of Surgery begins application r‐Hu EPO. Application r‐Hu EPO in patients with a terminal stage chronic renal insufficiency in 90–95% of cases had a positive effect, but 5–10% of patients have intolerance to erythropoietin, that has induced to search of new effective methods of correction of anemia. During research were determined quantity erythrocytes, hemoglobin, reticulocyte in peripheral blood and acid‐alkaline condition of blood. All hematology parameters were defined at the beginning of treatment, over 5 day and for 15 day of stimulation of a bone marrow. For 15 days after stimulation of a bone marrow by the laser there was an authentic increase of quantity erythrocyte, hemoglobin, hematocrit. The initial contents erythrocytes made 2.22 ± 0.1 10 × 12, hemoglobin 67.7 ± 3.2 g/l and hematocrit 18.2 ± 1.2%. During treatment by the laser parameters erythrocytes have increased up to 2.9 ± 0.8 10 × 12, hemoglobin up to 89.6 ± 2.9 g/l and hematocrit up to 28.2 ± 1.3%(P < 0,005). Hematology parameters in blood of control group authentically have not changed.
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