镧系掺杂上转换发光纳米材料的研究进展

上转换发光纳米材料在生物分析和医学成像中具有优异的应用前景。对上转换过程的研究正迅速发展为光化学、生物物理学、固体物理学和材料学的交叉领域。与有机荧光染料和量子点相比，镧系掺杂纳米晶体在生物荧光标记方面具有更少的限制条件。概述了镧系掺杂纳米晶体的结构和上转换发光机理，综述了镧系掺杂上转换发光纳米材料的合成、发光颜色调控方法及其生物分析应用方面的研究进展。

Research Progress of Lanthanide-Doped Upconversion Nanocrystals

Lanthanide-doped upconversion nanocrystals have remarkable potential utility in the fields of bio- logical assays and medical imaging. The study of these upconversion processes has evolved into a highly inter- disciplinary field that has rapidly expanded at the frontiers of photochemistry, biophysics, solid state physics, and materials science. In particular,upconversion emission from lanthanide-doped nanoerystals offers an attrac- tive optical labeling technique in biological studies without many of the constraints as contracted with organic fluorophores and quantum dots. This review aims to highlight the advances in the structures,the principle for upconversion emission, preparations, the adjusting method of emission colour and the applications to the bioana- lyrical studies of lanthanide-doped upconversion nanocrystals.