中美部分品牌烟草制品TSNA及其前体物的含量和关系

目的]初步了解中美市售部分烟草制品TSNA及其前体物的含量及关系,为雪茄安全性研究提供参考.方法]收集了中美市售卷烟及雪茄共37款烟草制品,对其TSNA以及其前体物含量进行测定,并进行相关分析.结果](1)烟碱转化率美国雪茄最高,平均5.50％,中式卷烟样本烟碱转化率最低,平均为2.83％,且与美国雪茄样本存在显...

The correlation between TSNAs content and their precursors content in some tobacco products on Chinese and the United States' markets

  Backgrounds  A preliminary understanding of the relationship of TSNAs content and their precursors content in some tobacco products sold in China and the United States will provide references for cigar safety research.  Methods  A total of 37 tobacco products, including cigarettes and cigars on the market in China and the United States were collected, and the contents of TSNAs and their precursors were determined and analyzed.  Results  (1) The nicotine conversion rate of American cigars is the highest, with an average of 5.50%; in contrast, the nicotine conversion rate of Chinese cigarette samples is the lowest, with an average of 2.83%, indicating a very significant difference. (2) The nitrate content of American cigars is the highest, with an average of 11.69 mg/g, while that of Chinese cigarettes is the lowest, with an average of 0.75 mg/g. The nitrate content of American cigarettes is about 7.7 times of that of Chinese cigarettes. (3) TSNA content of cigars is greater than cigarettes, the average amount of total TSNA of American and Chinese cigars are 20.62 and 19.86 μg/g, respectively; Chinese cigarettes have the lowest TSNA content, which is only 0.25 μg/g, and American cigarettes contain approximately 18 times that of Chinese cigarettes. (4) Nicotine conversion rate and nitrate content have a very significant positive correlation. Nitrate content has a significant positive correlation with NNK content, and a very significant positive correlation with other TSNAs content. The correlation between nitrite content and the contents of NAB, NNK and total TSNAs is extremely significant. Anatabine content has a very significant negative correlation with all TSNAs contents.  Conclusion  The contents of nitrate, nitrite and PNC has a strong correlation with the content of TSNA, and the safety of cigar tobacco products still needs to be improved.