| 基于Web的代谢网络仿真环境 |
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| 引用本文： | 张升蓉,罗若愚,刘谦,李亦学,骆清铭.基于Web的代谢网络仿真环境[J].计算机工程与应用,2006,42(36):97-99. |
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| 作者姓名： | 张升蓉 罗若愚 刘谦 李亦学 骆清铭 |
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| 作者单位： | 1. 华中科技大学,生物医学光子学教育部重点实验室-湖北省生物信息与分子成像重点实验室,武汉,430074
2. 上海生物信息技术研究中心,上海,200233 |
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| 基金项目： | 国家高技术研究发展计划(863计划);教育部科技基础条件平台建设项目 |
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| 摘 要： | 针对实时服务的需求和大规模代谢网络的大计算量,构建了一个基于集群系统的多层体系结构的代谢网络仿真环境,主要采用Applet技术、系统生物学描述语言(SBML)、Servlet与Applet之间的通信技术、线程池技术和负载平衡机制来实现。基于这个仿真环境,结合已有的代谢网络仿真技术,提供了一个远程在线的代谢网络的仿真服务。该仿真环境不仅便于升级和维护,而且具有平台无关性、强大的计算性能和对重负荷的支持能力。
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| 关 键 词： | 多层体系结构 Applet Servlet SBML 线程池 负载平衡机制 |
| 文章编号： | 1002-8331（2006）36-0097-03 |
| 收稿时间： | 2006-06 |
| 修稿时间： | 2006-06 |
Metabolic Network Simulation Environment Based on Web |
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| ZHANG Sheng-rong,LUO Ruo-yu,LIU Qian,LI Yi-xue,LUO Qing-ming.Metabolic Network Simulation Environment Based on Web[J].Computer Engineering and Applications,2006,42(36):97-99. |
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| Authors: | ZHANG Sheng-rong LUO Ruo-yu LIU Qian LI Yi-xue LUO Qing-ming |
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| Affiliation: | 1.The Key Laboratory of Biomedical Photonics of Ministry of Education-Hubei Bioinformatics and Molecular Imaging Key Laboratory,Huazhong University of Science and Technology,Wuhan 430074,China; 2.Shanghai Center for Bioinformation Technology, Shanghai 200233,China |
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| Abstract: | To the demand of real-time service and a great deal of computer by large-scale metabolic network,a metabolic network simulation environment of muti-layers framework based on cluster is constructed.Using Applet,SBML(Systems Biology Markup Language),the communication between Servlet and Applet,thread pool and Load balancing,the environment is completed.Based the environment and technology of metabolic network simulation,the on-line service of simulation is provided.The framework is not only convenient to be maintained and upgraded,but also has the independent of platform,the strong computational ability and the sustainability to the heavy traffic. |
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| Keywords: | Applet Servlet SBML |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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