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Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs |
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| Authors: | Shrilatha Balakrishna Jordy Saravia Paul Thevenot Terry Ahlert Slawo Lominiki Barry Dellinger and Stephania A Cormier |
| Affiliation: | (1) Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA;(2) Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana, USA;(3) Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA |
| Abstract: | BackgroundIncreased asthma risk/exacerbation in children and infants is associated with exposure to elevated levels of ultrafine particulate matter (PM). The presence of a newly realized class of pollutants, environmentally persistent free radicals (EPFRs), in PM from combustion sources suggests a potentially unrecognized risk factor for the development and/or exacerbation of asthma. |
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