Pharmacokinetics of doxycycline after parenteral administration in the Houbara bustard (Chlamydotis undulata) |
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Authors: | A Greth H Gerlach H Gerbermann M Vassart P Richez |
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Affiliation: | Department of Obstetrics and Gynecology, School of Medicine, University of Tokushima, Japan. |
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Abstract: | Human seminal plasma contains a protein with an estimated molecular weight of 16 kd that binds serum immunoglobulin gamma (IgG) and is named IgG binding factor (IgBF). Purified IgBF specifically suppressed pokeweed mitogen-induced lymphocyte blastogenesis, having little or no effect on lymphocyte blastogenesis stimulated with phytohemagglutinin or Concanavalin A; antibody-dependent cell-mediated cytotoxicity; natural killer cell activity; or complement-dependent cytotoxicity of antibodies against sperm. It would appear that IgBF may suppress activation of B cells in the male and female genital tract. |
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